Selected publications
Primary research articles
Review articles
Primary research
- H. Fernando, S. Sewitz, J. Darot, S. Tavaré, J.L. Huppert, and S. Balasubramanian
Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression
Nucl. Ac. Res. (2009) In press
link - K.J. Neaves, J.L. Huppert, R.M. Henderson and J. Michael Edwardson
Direct visualization of G-quadruplexes in DNA using atomic force microscopy
Nucl. Ac. Res. (2009) In press
Link - O. Stegle, L. Payet, J.-L. Mergny, D.J.C. MacKay and J. L. Huppert
Predicting and understanding the stability of G-quadruplexes
Bioinformatics (2009) 25 i374-i382
Link - H.M. Wong and J. L. Huppert
Stable G-quadruplexes are found outside nucleosome-bound regions
Mol. Biosyst. (2009) In press
Link - J.L. Huppert, A. Bugaut, S. Kumari, S. Balasubramanian
G-quadruplexes: the beginning and end of UTRs
Nucl. Ac. Res. (2008) 36 6260-8
Link - J.L. Huppert
Thermodynamic prediction of RNA/DNA duplex-forming regions in the human genome
Mol. BioSyst. (2008) 4 686-691
Link - The ENCODE consortium
The ENCODE pilot project: functional annotation of 1% of the human genome
Nature (2007) 447 799-816
Link - S. Kumari, A. Bugaut, J.L. Huppert, S. Balasubramanian
An RNA G-quadruplex in the 5'-UTR of a proto-oncogene regulates translation
Nat. Chem. Biol. (2007) 3 218-221
Link. News and views article here. - J.L. Huppert and S. Balasubramanian
G-quadruplexes in promoters throughout the human genome
Nucl. Ac. Res. (2007) 35 406-413
Link. Article in 'The Scientist' here - H. Fernando, A.P. Reszka, J.L. Huppert, S. Ladame, S. Rankin, A.R. Venkitaraman, S. Neidle and S. Balasubramanian
A Conserved Quadruplex Motif Located in a Transcription Activation Site of the Human c-kit Oncogene
Biochemistry (2006) 45 7854-7860
Link - S. Rankin, A. P. Reszka, J.L. Huppert, M. Zloh, G. N. Parkinson, A. K. Todd, S. Ladame, S. Balasubramanian and S. Neidle
Putative DNA quadruplex formation within the human c-kit oncogene
J. Am. Chem. Soc. (2005) 127 10584-9
Link - J.L. Huppert and S. Balasubramanian
Prevalence of quadruplexes in the human genome
Nucl. Ac. Res. (2005) 33 2908-2916
Link - P. Hazel, J.L. Huppert, S. Balasubramanian and S. Neidle
Loop-length-dependent folding of G-quadruplexes
J. Am. Chem. Soc. (2004) 126 16405-15
Link
Reviews
- B.-S. Herbert, J.L. Huppert, F.B. Johnson, A.N. Lane and A.T. Phan
Meeting report: Second international meeting on quadruplex DNA
Biochimie (2009) 91 1059
Link - A. Lister, V. Charoensawan, S. De, K. James, S.C. Janga and J. Huppert
Interfacing systems biology and synthetic biology
Genome Biology (2009) 10 309
Link - H.M. Wong, L. Payet and J.L. Huppert
Function and targeting of G-quadruplexes
Curr. Op. Mol. Ther. (2009) 11 146-55
Link - J.L. Huppert
Four-stranded nucleic acids: structure, function and targeting of G-quadruplexes
Chem. Soc. Rev. (2008) 37 1375-1384
Link - J.L. Huppert
Hunting G-quadruplexes
Biochimie (2008) 90 1140-8
Link - J.L. Huppert
Four-stranded DNA: Cancer, gene regulation and drug development
Phil Trans Roy Soc A, Triennial edition (2007) 365 2969-2984
Link - J.L. Huppert
Genomic Quadruplexes
in Quadruplex Nucleic Acids (2006)
S. Neidle and S. Balasubramanian Eds
Royal Society of Chemistry publications, ISBN 0 85404 374 8
Link
