Dr. Rosana Collepardo has been awarded a €1.5 million ERC starting grant to develop a novel multi-scale computational method to investigate the organization of the genome with sub-nucleosome resolution.
While sequencing our genome today is easy, finding out how it functions remains an urgent unsolved problem crucial to rationalise normal and aberrant cell behaviour. The 3D organization of the genome is intimately linked to its function. However, the next big challenge in the field of genomic sciences is deciphering (a) how the genome is organized in space and (b) how this organization influences its function. This ERC project aims at driving the transformation of our ability to understand how genomes function by pushing the current limits of realistic computational modelling of in vivo chromatin structure.
Well done Rosana, very well deserved!